Topical therapies in hyperhidrosis care.

Abstract

Primary focal hyperhidrosis affects 3% of the US population; about the same number as psoriasis. More than half of these patients have primary focal axillary hyperhidrosis: sweating that is beyond what is anticipated or necessary for thermoregulation. Most topical therapies are based on aluminum salts, which work by a chemical reaction that forms plugs in the eccrine sweat ducts. Topical anticholinergics may also be used. Instruction on proper methods and timing of antiperspirants enhances effect and may be effective alone or in combination with other treatments in patients with hyperhidrosis.

• Authors: David M Pariser, Angela Ballard
• Journal: Dermatologic clinics (Dermatol Clin) Vol. 32 Issue 4 Pg. 485-90 (Oct 2014) ISSN: 1558-0520 [Electronic] United States
• PMID: 25152341 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2014 Elsevier Inc. All rights reserved.

Chemical References

• Aluminum Compounds
• Cholinergic Antagonists

Topics

• Administration, Topical
• Aluminum Compounds (administration & dosage)
• Cholinergic Antagonists (administration & dosage)
• Humans
• Hyperhidrosis (drug therapy, physiopathology)
• Sweating (drug effects)