[Idiopathic choroidal neovascularization--case report].

Abstract

PURPOSE:

To report a patient with peripapillary idiopathic choroidal neovascularization treated with an anti-VEGF (anti- vascular endothelial growth factor) agent (bevacizumab) observed during for 9 months.

PATIENT AND METHODS:

Twenty nine years old man was referred to the Department for diagnosis and treatment because of unilateral visual acuity decrease in the right eye (VA RE--0.1) and metamorphopsias. The routine ophthalmic examination revealed macular edema and peripapillaryedema with epiretinal and intraretinal hemorrhages. The optical coherence tomography, fluorescein angiography, as well as laboratory tests were performed in order to exclude uveitis. Due to the difficulties in the diagnosis indocyanine green angiography was also performed. Based on clinical symptoms and the findings of the additional diagnostic procedures, the patient was diagnosed with idiopathic choroidal neovascularization. The patient was qualified for anti-VEGF therapy and received three intravitreal injections of bevacizumab at the dose of 1.25 mg, at monthly intervals.

RESULTS:

Significant improvement of visual acuity (VA RE - 1.0) and regression of the peripapillary edema with hemorrhages were achieved after the third injection of 1.25 mg bevacizumab. At 6 months, peripapillary scarring was observed in the area involved by the primary lesions.

CONCLUSIONS:

Anti-VEGF therapy is the effective treatment of idiopathic choroidal neovascularization in the described case. The visual acuity improvement and rapid regression of posterior segment lesions after bevacizumab administration were observed.

• Authors: Ewelina Lachowicz, Katarzyna Kubasik-Kładna, Katarzyna Mozolewska-Piotrowska, Wojciech Lubiński
• Journal: Klinika oczna (Klin Oczna) Vol. 116 Issue 1 Pg. 35-8 ( 2014) ISSN: 0023-2157 [Print] Poland
• Vernacular Title: Idiopatyczna neowaskularyzacja podsiatkówkowa--opis przypadku.
• PMID: 25137920 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Angiogenesis Inhibitors
• Antibodies, Monoclonal, Humanized
• Vascular Endothelial Growth Factor A
• Bevacizumab

Topics

• Adult
• Angiogenesis Inhibitors (administration & dosage)
• Antibodies, Monoclonal, Humanized (administration & dosage)
• Bevacizumab
• Choroidal Neovascularization (diagnosis, drug therapy)
• Follow-Up Studies
• Humans
• Male
• Tomography, Optical Coherence
• Vascular Endothelial Growth Factor A (antagonists & inhibitors)
• Visual Acuity