Abstract |
Gastric adenosquamous carcinoma is a rare malignancy with a poor prognosis. We recently performed palliative gastrectomy for a gastric adenosquamous carcinoma with peritoneal dissemination and provided a course of systemic chemotherapy with S-1 plus paclitaxel(PTX)after the surgery. No serious adverse events were observed, and treatment with S-1 plus PTX was continued for 1 year before being switched to adjuvant chemotherapy with S-1 alone for another year. The tumor maker levels normalized within 2 months of the initial treatment, and the peritoneal dissemination could no longer be detected by abdominal computed tomography(CT). The patient remained in clinical remission and maintained long-term survival of over 8 years.
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Authors | Masamitsu Hirano, Yuki Ozamoto, Masumi Ichinose, Takeshi Togawa, Nobuyuki Takao, Akiyoshi Mizumoto, Manami Tatsuno, Yoshihiro Yamamoto, Yutaka Yonemura |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 41
Issue 7
Pg. 885-8
(Jul 2014)
ISSN: 0385-0684 [Print] Japan |
PMID | 25131877
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Drug Combinations
- S 1 (combination)
- Tegafur
- Oxonic Acid
- Paclitaxel
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Topics |
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Biopsy
- Carcinoma, Adenosquamous
(drug therapy, surgery)
- Chemotherapy, Adjuvant
- Drug Combinations
- Gastrectomy
- Humans
- Male
- Oxonic Acid
(administration & dosage)
- Paclitaxel
(administration & dosage)
- Peritoneal Neoplasms
(drug therapy, secondary)
- Stomach Neoplasms
(drug therapy, pathology, surgery)
- Tegafur
(administration & dosage)
- Time Factors
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