Successful outcome of renal transplantation in a child with HIV-associated nephropathy.

Abstract

Classical HIV-associated nephropathy (HIVAN) was first described before the advent of highly active antiretroviral therapy in late stages of HIV disease with high viral load and low CD4 cell count. Renal transplantation has been successful in a large series of carefully selected HIV-infected adults, with patient and renal allograft survival approaching those of non-HIV-infected patients. We report the successful outcome of living related renal transplantation in a vertically transmitted HIV-infected 8-year-old girl with end-stage kidney disease on haemodialysis due to HIVAN. The pretransplant preparations and post-transplant care, with particular emphasis on immunosuppression and avoidance of opportunistic infections, are discussed.

• Authors: Rukshana C Shroff, Mignon McCulloch, Vas Novelli, Delane Shingadia, Suzanne Bradley, Margaret Clapson, Nizam Mamode, Stephen D Marks
• Journal: Archives of disease in childhood (Arch Dis Child) Vol. 99 Issue 11 Pg. 1026-8 (Nov 2014) ISSN: 1468-2044 [Electronic] England
• PMID: 25123405 (Publication Type: Case Reports, Journal Article)
• Copyright: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Topics

• AIDS-Associated Nephropathy (surgery)
• Child
• Female
• HIV Infections (complications, surgery)
• Humans
• Kidney Failure, Chronic (complications, surgery)
• Kidney Transplantation (methods)
• Treatment Outcome