Abstract | BACKGROUND: METHODS: Refractory corneal perforations in ten patients (10 eyes) with severe SJS were mended with a minimal corneal patch graft, under the guidance of anterior chamber optical coherence tomography, combined with conjunctival flap covering. The outcome measures included healing of the corneal perforation, survival of the corneal graft and conjunctival flap, relevant complications, and improvement in visual acuity. RESULTS:
Corneal perforation healed, and global integrity was achieved in all eyes. No immune rejection or graft melting was detected. Retraction of conjunctival flap occurred in one eye, which was treated with additional procedure. Visual acuity improved in six eyes (60%), unchanged in three eyes (30%) and declined in one eye (10%). CONCLUSIONS: The MSTK combined with conjunctival flap covering seems to be effective for refractory corneal perforation in severe SJS.
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Authors | Fuhua Wang, Suxia Li, Ting Wang, Hua Gao, Weiyun Shi |
Journal | BMC ophthalmology
(BMC Ophthalmol)
Vol. 14
Pg. 97
(Aug 08 2014)
ISSN: 1471-2415 [Electronic] England |
PMID | 25102918
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Anterior Chamber
(pathology)
- Conjunctiva
(transplantation)
- Corneal Perforation
(diagnosis, etiology, surgery)
- Female
- Follow-Up Studies
- Graft Survival
- Humans
- Keratoplasty, Penetrating
(methods)
- Male
- Middle Aged
- Retrospective Studies
- Stevens-Johnson Syndrome
(complications, diagnosis)
- Surgical Flaps
- Tomography, Optical Coherence
- Treatment Outcome
- Visual Acuity
- Young Adult
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