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Bilateral choroidal osteoma with choroidal neovascular membrane treated with bevacizumab in a child.

Abstract
Choroidal osteoma is a rare benign tumor. We report a male child diagnosed with bilateral choroidal osteoma, high myopia and secondary choroidal neovascularization (CNV) membrane in one eye. Co-existence of posterior staphyloma made the clinical diagnosis of choroidal osteoma difficult due to the osteoma filling the depression of the posterior staphyloma. Typical findings on fundus fluorescein angiography, optical coherence tomography, B-scan and indocyanine green angiography confirmed the diagnosis. A review of literature was performed. CNV secondary to choroidal osteoma was treated with intravitreal bevacizumab and it responded well. Regular follow-up is essential for recurrence of CNV and decalcification of the osteoma.
AuthorsManisha Agarwal, Meha Kantha, Rahul Mayor, Ramesh Venkatesh, Cyrus M Shroff
JournalMiddle East African journal of ophthalmology (Middle East Afr J Ophthalmol) 2014 Jul-Sep Vol. 21 Issue 3 Pg. 265-7 ISSN: 0975-1599 [Electronic] India
PMID25100914 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Angiogenesis Inhibitors
  • Antibodies, Monoclonal, Humanized
  • VEGFA protein, human
  • Vascular Endothelial Growth Factor A
  • Bevacizumab
Topics
  • Angiogenesis Inhibitors (therapeutic use)
  • Antibodies, Monoclonal, Humanized (therapeutic use)
  • Bevacizumab
  • Child
  • Choristoma (diagnosis, drug therapy)
  • Choroid Neoplasms (diagnosis, drug therapy)
  • Choroidal Neovascularization (diagnosis, drug therapy)
  • Fluorescein Angiography
  • Humans
  • Male
  • Osteoma (diagnosis, drug therapy)
  • Tomography, Optical Coherence (methods)
  • Vascular Endothelial Growth Factor A (antagonists & inhibitors)

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