Abstract | OBJECTIVE: STUDY DESIGN: Prospective clinical trial. SETTING: Single tertiary care centre. PARTICIPANTS: Thirty-five children (14 boys and 21 girls) participated in this study. MAIN OUTCOME MEASURES: The operations were performed with the indication of sleep-disordered breathing (SDB). Blood samples were taken preoperatively and at 6 months postoperatively to determine the changes in serum high-sensitivity CRP ( hs-CRP), IL-6, fetuin-A, cystatin C, adiponectin and TNF-α levels. Pre- and postoperative values of body weights and heights of the participants were recorded preoperatively and at postoperative 6 months. RESULTS: Patients underwent adenoidectomy (n = 21) or adenotonsillectomy (n = 21). The mean age at surgery was 8.74 ± 3.33 years (range 3-16 years). Mean serum levels of parameters measured preoperatively and at postoperative 6 months. The observed differences between pre- and postoperative values were statistically significant (P < 0.05), excluding cystatin C levels (P > 0.05). CONCLUSION:
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Authors | M Mutlu, E Vuralkan, S Yardim Akaydin, I Akin, E Miser |
Journal | Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
(Clin Otolaryngol)
Vol. 39
Issue 5
Pg. 266-71
(Oct 2014)
ISSN: 1749-4486 [Electronic] England |
PMID | 25099745
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2014 John Wiley & Sons Ltd. |
Chemical References |
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Topics |
- Adenoidectomy
- Adolescent
- Child
- Child, Preschool
- Female
- Follow-Up Studies
- Humans
- Inflammation Mediators
(blood)
- Male
- Prospective Studies
- Sleep Apnea, Obstructive
(immunology, surgery)
- Snoring
(immunology, surgery)
- Tonsillectomy
- Turkey
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