One-year outcome of subacromial corticosteroid injection compared with manual physical therapy for the management of the unilateral shoulder impingement syndrome: a pragmatic randomized trial.

Abstract

BACKGROUND:

Corticosteroid injections (CSIs) and physical therapy are used to treat patients with the shoulder impingement syndrome (SIS) but have never been directly compared.

OBJECTIVE:

To compare the effectiveness of 2 common nonsurgical treatments for SIS.

DESIGN:

Randomized, single-blind, comparative-effectiveness, parallel-group trial. (ClinicalTrials.gov: NCT01190891).

SETTING:

Military hospital-based outpatient clinic in the United States.

PATIENTS:

104 patients aged 18 to 65 years with unilateral SIS between June 2010 and March 2012.

INTERVENTION:

Random assignment into 2 groups: 40-mg triamcinolone acetonide subacromial CSI versus 6 sessions of manual physical therapy.

MEASUREMENTS:

The primary outcome was change in Shoulder Pain and Disability Index scores at 1 year. Secondary outcomes included the Global Rating of Change scores, the Numeric Pain Rating Scale scores, and 1-year health care use.

RESULTS:

Both groups demonstrated approximately 50% improvement in Shoulder Pain and Disability Index scores maintained through 1 year; however, the mean difference between groups was not significant (1.5% [95% CI, -6.3% to 9.4%]). Both groups showed improvements in Global Rating of Change scale and pain rating scores, but between-group differences in scores for the Global Rating of Change scale (0 [CI, -2 to 1]) and pain rating (0.4 [CI, -0.5 to 1.2]) were not significant. During the 1-year follow-up, patients receiving CSI had more SIS-related visits to their primary care provider (60% vs. 37%) and required additional steroid injections (38% vs. 20%), and 19% needed physical therapy. Transient pain from the CSI was the only adverse event reported.

LIMITATION:

The study occurred at 1 center with patients referred to physical therapy.

CONCLUSION:

Both groups experienced significant improvement. The manual physical therapy group used less 1-year SIS-related health care resources than the CSI group.

PRIMARY FUNDING SOURCE:

Cardon Rehabilitation Products through the American Academy of Orthopaedic Manual Physical Therapists.

• Authors: Daniel I Rhon, Robert B Boyles, Joshua A Cleland
• Journal: Annals of internal medicine (Ann Intern Med) Vol. 161 Issue 3 Pg. 161-9 (Aug 05 2014) ISSN: 1539-3704 [Electronic] United States
• PMID: 25089860 (Publication Type: Comparative Study, Journal Article, Pragmatic Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents
• Triamcinolone Acetonide

Topics

• Adolescent
• Adult
• Aged
• Anti-Inflammatory Agents (therapeutic use)
• Female
• Humans
• Injections, Intra-Articular
• Male
• Middle Aged
• Physical Therapy Modalities
• Shoulder Impingement Syndrome (drug therapy, therapy)
• Single-Blind Method
• Treatment Outcome
• Triamcinolone Acetonide (therapeutic use)
• Young Adult