Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss.

Abstract

Neuromyelitis optica (NMO) is an autoimmune astrocytopathy caused by anti-aquaporin 4 antibody. Only two patients with NMO have been reported presenting with hearing disorders to our knowledge. We recently treated a 40-year-old woman with NMO complaining of right hearing loss. Audiometry showed minimal asymmetry, but the auditory brainstem responses (ABR) were severely attenuated on the right. The attenuated ABR and her aural symptoms (hearing loss and fullness) improved after steroid treatment. The present case shows that the retrocochlear-type hearing loss may be associated with NMO.

• Authors: Yoshitaka Takanashi, Tatsuro Misu, Kazuha Oda, Hiromitsu Miyazaki, Izumi Yahata, Hiroshi Hidaka, Kazuo Fujihara, Tetsuaki Kawase, Toshimitsu Kobayashi, Yukio Katori
• Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia (J Clin Neurosci) Vol. 21 Issue 12 Pg. 2249-51 (Dec 2014) ISSN: 1532-2653 [Electronic] Scotland
• PMID: 25085730 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2014 Elsevier Ltd. All rights reserved.

Chemical References

• Steroids

Topics

• Adult
• Evoked Potentials, Auditory, Brain Stem (drug effects, physiology)
• Female
• Functional Laterality
• Hearing Loss (drug therapy, pathology, physiopathology)
• Humans
• Magnetic Resonance Imaging
• Neuromyelitis Optica (drug therapy, pathology, physiopathology)
• Steroids (therapeutic use)