Abstract | OBJECTIVE: GG) METHODS: 40 children referred to tympanostomy were randomized to receive either L. GG or placebo (1:1) for 3 weeks before surgery. MEE samples were collected from 13 children (in total, 25 samples, 19 from the L. GG group and 6 from the placebo group) and analyzed for L. GG and pathogenic bacterial and viral findings. RESULTS: L. GG was present in 5 of the 25 MEE samples (4 from the L. GG group). Haemophilus infuenzae was the most prominent pathogen in 12 samples (10 from the L. GG group). Rhinovirus was present in 12 samples (10 from the L. GG group) and enterovirus in 1 sample (L. GG group). CONCLUSIONS: L. GG was present in the middle ear of children suffering from otitis media with effusion, but did not reduce the presence of pathogenic bacteria or viruses.
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Authors | Laura Tapiovaara, Liisa Lehtoranta, Elisa Swanljung, Harri Mäkivuokko, Sanna Laakso, Merja Roivainen, Riitta Korpela, Anne Pitkäranta |
Journal | International journal of pediatric otorhinolaryngology
(Int J Pediatr Otorhinolaryngol)
Vol. 78
Issue 10
Pg. 1637-41
(Oct 2014)
ISSN: 1872-8464 [Electronic] Ireland |
PMID | 25085073
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 Elsevier Ireland Ltd. All rights reserved. |
Topics |
- Administration, Oral
- Child
- Child, Preschool
- Double-Blind Method
- Ear, Middle
(microbiology)
- Exudates and Transudates
- Humans
- Lacticaseibacillus rhamnosus
(chemistry)
- Male
- Otitis Media with Effusion
(drug therapy, microbiology)
- Probiotics
(administration & dosage, therapeutic use)
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