Abstract | OBJECTIVE: SETTING-INTERVENTIONS: RESULTS: Among 42 of the enrolled patients with thrombocytopenia-associated multiple organ failure, all had a primary or secondary sepsis diagnosis. Fifteen received plasma exchange therapy (PE [+] group) and 27 received standard medical treatment without plasma exchange (PE [-] group). The mean age was 17.69 months (8.24-54.22) in the PE (+) group and 13.46 months (6.47-20.55) in the PE (-) group. Age (p = 0.232), gender (p = 0.206), thrombocyte count (p = 0.09), Organ Failure Index score (p = 0.111), and pediatric logistic organ dysfunction score (p = 0.177) at admission were not statistically different between groups. The overall 28-day mortality was higher in the PE (-) group (70.37%) compared with the PE (+) group (26.67%) (univariate p = 0.006; multivariate controlling for pediatric logistic organ dysfunction, Organ Failure Index, Pediatric Risk of Mortality scores, and neurological failure p = 0.048). Length of stay was increased in the PE (+) group (p = 0.004). CONCLUSIONS:
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Authors | Esra Sevketoglu, Dincer Yildizdas, Ozden Ozgur Horoz, Hasan Serdar Kihtir, Tanil Kendirli, Suleyman Bayraktar, Joseph A Carcillo |
Journal | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
(Pediatr Crit Care Med)
Vol. 15
Issue 8
Pg. e354-9
(Oct 2014)
ISSN: 1529-7535 [Print] United States |
PMID | 25068251
(Publication Type: Journal Article, Multicenter Study, Observational Study)
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Topics |
- Child, Preschool
- Female
- Humans
- Infant
- Length of Stay
- Male
- Multiple Organ Failure
(etiology, therapy)
- Plasma Exchange
- Retrospective Studies
- Sepsis
(complications)
- Survival Rate
- Thrombocytopenia
(complications, therapy)
- Treatment Outcome
- Turkey
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