Abstract | BACKGROUND AND PURPOSE: We investigated the relationship between transcranial Doppler (TCD) pulsatility index (PI) and central aortic pressure by measurement of the aortic augmentation index (AIx). METHODS: We enrolled 148 consecutive patients with a diagnosis of acute ischemic stroke. Patients were eligible for the study if they experienced their first ischemic stroke within the preceding 7 days and were 45 years of age or older. At Day 7 (±2) after stroke onset, TCD studies were performed and AIx was measured by applanation tonometry on the same days. RESULTS: The mean age was 66.3 (47-90) years and 37.8% were women. The mean middle cerebral artery (MCA) PI was significantly related with age (r =.361), hypertension (r = .184), peripheral systolic blood pressure (SBP; r = .211), peripheral pulse pressure (PP; r = .396), aortic SBP (r = .184), aortic DBP (r = -.181), and aortic PP (r = .371). The basilar artery (BA) PI was significantly related with age (r = .311), peripheral DBP (r = -.267), peripheral PP (r = .358), aortic DBP (r = -.266), and aortic PP (r = .347). CONCLUSIONS: TCD PI was significantly related with central aortic pressure, especially PP. The PI in the MCA and BA is closely associated with the pulsatile component of BP in the systemic circulation.
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Authors | Jeong Yeon Kim, Cheryl D Bushnell, Joong Hyun Park, Seung Min Han, Jin Hee Im, Sang Won Han, Jong Sam Baik, Jae Hyeon Park |
Journal | Journal of neuroimaging : official journal of the American Society of Neuroimaging
(J Neuroimaging)
2015 May-Jun
Vol. 25
Issue 3
Pg. 438-42
ISSN: 1552-6569 [Electronic] United States |
PMID | 25060557
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 by the American Society of Neuroimaging. |
Topics |
- Aged
- Arterial Pressure
- Blood Pressure
- Cerebral Arteries
(diagnostic imaging, physiopathology)
- Female
- Humans
- Image Interpretation, Computer-Assisted
(methods)
- Male
- Middle Aged
- Pulsatile Flow
- Reproducibility of Results
- Sensitivity and Specificity
- Statistics as Topic
- Stroke
(diagnostic imaging, physiopathology)
- Ultrasonography, Doppler, Transcranial
(methods)
- Vascular Resistance
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