Electrochemical device based on a Pt nanosphere-paper working electrode for in situ and real-time determination of the flux of H2O2 releasing from SK-BR-3 cancer cells.

Abstract	A novel paper working electrode with Pt nanospheres grown in it (Pt-PWE) was first used as a sensor platform and then cancer cells were immobilized on the Pt-PWE (high affinity binding with aptamers). This electrode was first designed to achieve the in situ and real-time determination of H2O2 released from cancer cells to obtain an accurate determination.
Authors	Fang Liu, Shenguang Ge, Jinghua Yu, Mei Yan, Xianrang Song
Journal	Chemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 50 Issue 71 Pg. 10315-8 (Sep 14 2014) ISSN: 1364-548X [Electronic] England
PMID	25058322 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Antineoplastic Agents Platinum Hydrogen Peroxide
Topics	Antineoplastic Agents (pharmacology) Apoptosis (drug effects, physiology) Breast Neoplasms (chemistry, metabolism) Cell Line, Tumor Electrochemical Techniques (methods) Electrodes Female Humans Hydrogen Peroxide (analysis, metabolism) Nanospheres (chemistry) Paper Platinum (chemistry)

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