[Investigation of Triazavirin antiviral activity against tick-borne encephalitis pathogen in cell culture].

Abstract

The efficacy of Triazavirin against the tick-borne encephalitis virus was estimated in the sensitive cell culture vs. the active drug Ribavirin. In a concentration of 128 mcg/ml Triazavirin was shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.

• Authors: S Ia Loginova, S V Borisevich, V L Rusinov, U N Ulomskiĭ, V N Charushin, O N Chupakhin
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 59 Issue 1-2 Pg. 3-5 ( 2014) ISSN: 0235-2990 [Print] Russia (Federation)
• PMID: 25051708 (Publication Type: Journal Article)

Chemical References

• Antiviral Agents
• Azoles
• Triazines
• Triazoles
• Ribavirin
• riamilovir

Topics

• Animals
• Antiviral Agents (chemical synthesis, pharmacology)
• Azoles (chemical synthesis, pharmacology)
• Cell Line
• Encephalitis Viruses, Tick-Borne (drug effects, physiology)
• Epithelial Cells (cytology, drug effects, virology)
• Kidney (cytology, drug effects, virology)
• Ribavirin (pharmacology)
• Swine
• Triazines (chemical synthesis, pharmacology)
• Triazoles
• Virus Replication (drug effects)