Abstract | PURPOSE: METHODS: Between May 2010 and April 2012, 30 patients with head and neck SCC underwent preoperative DWI and CTP. Two radiologists measured apparent diffusion coefficient (ADC) values and CTP parameters independently. Surgery and histopathologic examinations were performed on all patients. RESULTS: On DWI, 65 LNs were detected in 30 patients. The mean ADC value of metastatic nodes was lower than benign nodes and the difference was statistically significant (P < 0.05). On CTP images, the mean value in metastatic nodes of blood flow (BF) and blood volume (BV) was higher than that in benign nodes, and mean transit time (MTT) in metastatic nodes was lower than that in benign nodes. There were significant differences in BF and MTT values between metastatic and benign LNs (P < 0.05). There were significant differences between the AUCs of DWI and CTP (Z=4.612, P < 0.001). CONCLUSION: DWI with ADC value measurements may be more accurate than CTP for the preoperative diagnosis of cervical LN metastases.
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Authors | Jin Zhong, Zonghong Lu, Liang Xu, Longchun Dong, Hui Qiao, Rui Hua, Yi Gong, Zhenxing Liu, Caixian Hao, Xuehuan Liu, Changqing Zong, Li He, Jun Liu |
Journal | BioMed research international
(Biomed Res Int)
Vol. 2014
Pg. 260859
( 2014)
ISSN: 2314-6141 [Electronic] United States |
PMID | 25050333
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Carcinoma, Squamous Cell
(diagnostic imaging)
- Cervical Vertebrae
(diagnostic imaging, pathology)
- Diffusion Magnetic Resonance Imaging
- Female
- Head and Neck Neoplasms
(diagnostic imaging)
- Humans
- Lymphatic Metastasis
(diagnostic imaging)
- Male
- Middle Aged
- Perfusion
- Squamous Cell Carcinoma of Head and Neck
- Tomography, X-Ray Computed
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