Photodynamic therapy plus topical retinoids in Darier's disease.

Abstract

Darier's disease is a rare, genetically determined, chronic disorder of keratinization. Characterized clinically by a symmetrical eruption of hypercheratotic papules with predilection for the seborrhoeic areas of the body. Many treatments have been suggested: emollients, topical retinoids, dermoabrasion, topical steroids and intermittent courses of oral antibiotics. Systemic retinoids are usually the treatment of choice. We present a small case series of patients treated with PDT and topical retinoids with good results. This therapeutic modality could represent an alternative to systemic retinoid treatment.

• Authors: Paolo Amerio, Tommaso Gobello, Cinzia Mazzanti, Eugenia Giaculli, Salvatore Ruggeri, Donatella Sordi, Massimo Amatetti, Luca Chinni, Antonio Tulli
• Journal: Photodiagnosis and photodynamic therapy (Photodiagnosis Photodyn Ther) Vol. 4 Issue 1 Pg. 36-8 (Mar 2007) ISSN: 1572-1000 [Print] Netherlands
• PMID: 25047189 (Publication Type: Journal Article)