Abstract | PURPOSE: MATERIALS AND METHODS: Total RNA was isolated from serum. miRNA levels were quantified by quantitative real-time polymerase chain reaction. We assessed the miRNAs miR-302a-3p, 302b-3p, 302c-3p, 367-3p, 371a-3p, 372-3p and 373-3p in a subcohort of 30 patients with testicular germ cell tumor and 18 healthy subjects. Validation was performed in 76 patients treated with inguinal exploration due to suspicion of testicular germ cell tumor, of whom 59 had cancer and 17 had benign disease, and in 84 healthy male subjects. RESULTS: CONCLUSIONS:
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Authors | Isabella Syring, Joanna Bartels, Stefan Holdenrieder, Glen Kristiansen, Stefan C Müller, Jörg Ellinger |
Journal | The Journal of urology
(J Urol)
Vol. 193
Issue 1
Pg. 331-7
(Jan 2015)
ISSN: 1527-3792 [Electronic] United States |
PMID | 25046619
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Biomarkers, Tumor
- MicroRNAs
|
Topics |
- Biomarkers, Tumor
(blood)
- Humans
- Male
- MicroRNAs
(blood)
- Neoplasms, Germ Cell and Embryonal
(blood, pathology)
- Testicular Neoplasms
(blood, pathology)
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