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Esophageal adenocarcinoma with white opaque substance observed by magnifying endoscopy with narrow band imaging.

Abstract
White opaque substance (WOS) is observed in the gastric neoplasia of 0-IIa type using magnifying endoscopy with narrow band imaging (NBI-ME). Colonic and duodenal neoplasms with WOS have also been reported. Immunohistochemical examination with adipophilin reveals WOS in gastric neoplasms as lipid droplets, and WOS is specific for neoplasm with intestinal or gastrointestinal phenotype. We herein report a case of adenocarcinoma of the esophagogastric junction with WOS. A male patient in his sixties was found by esophagogastroduodenoscopy to have an esophageal elevated lesion. NBI-ME showed whitish deposits that looked similar to WOS in gastric neoplasms. The patient underwent endoscopic submucosal dissection and the lesion was resected in a single piece. This tumor had diffuse positivity for adipophilin and gastrointestinal phenotype.
AuthorsShunsuke Yoshii, Motohiko Kato, Keiichiro Honma, Tetsuji Fujinaga, Yoshiki Tsujii, Akira Maekawa, Takuya Inoue, Yoshito Hayashi, Tomofumi Akasaka, Shinichiro Shinzaki, Tsutomu Nishida, Hideki Iijima, Masahiko Tsujii, Eiichi Morii, Tetsuo Takehara
JournalDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society (Dig Endosc) Vol. 27 Issue 3 Pg. 392-6 (Mar 2015) ISSN: 1443-1661 [Electronic] Australia
PMID25041337 (Publication Type: Case Reports, Journal Article, Review)
Copyright© 2014 The Authors. Digestive Endoscopy © 2014 Japan Gastroenterological Endoscopy Society.
Topics
  • Adenocarcinoma (pathology, surgery)
  • Biopsy, Needle
  • Dissection (methods)
  • Esophageal Neoplasms (pathology, surgery)
  • Esophagogastric Junction (pathology)
  • Esophagoscopes
  • Esophagoscopy (instrumentation, methods)
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Narrow Band Imaging
  • Risk Assessment
  • Treatment Outcome

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