Abstract | OBJECTIVE: METHODS: The clinical records of 25 patients (mean age 69 years) diagnosed with carcinomatous pleuritis during a thoracotomy by pathological examination and followed by surgery between 1994 and 2012 were reviewed. The treatment modality, including surgery, the clinicopathologic characteristics and 5-year survival were analyzed. RESULTS: There were 16 adenocarcinomas, 6 squamous cell carcinomas and 3 large cell carcinomas. Surgery included resection of the main tumor by partial resection in 10 cases, segmentectomy in 2 cases, lobar resection in 12 cases and bilobectomy in 1 case. Intrathoracic irrigation was performed in 20 cases. The pathological N status was N0/N1/N2/Nx: 10/6/7/2. Fifteen patients received adjuvant therapy. The overall 5-year survival rate was 22.2 %. The 5-year survival rates of the N0, N1 and N2 groups were 36.0, 16.7 and 14.3 %, respectively (p = 0.0068). Nine patients lived more than 3 years including 5 in N0, 3 in N1 and 1 in N2. CONCLUSIONS: Surgery should not be excluded from the multi-modality treatment of patients with carcinomatous pleuritis because there are some patients who could benefit from surgery especially if they are in N0 status.
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Authors | Tetsuhiko Go, Noriyuki Misaki, Natsumi Matsuura, Sung Soo Chang, Shintarou Tarumi, Hiroyasu Yokomise |
Journal | Surgery today
(Surg Today)
Vol. 45
Issue 2
Pg. 197-202
(Feb 2015)
ISSN: 1436-2813 [Electronic] Japan |
PMID | 25034395
(Publication Type: Journal Article)
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Topics |
- Aged
- Carcinoma, Non-Small-Cell Lung
(complications, mortality, pathology, therapy)
- Combined Modality Therapy
- Female
- Humans
- Lung Neoplasms
(complications, mortality, pathology, therapy)
- Male
- Middle Aged
- Neoplasm Staging
- Pleura
(surgery)
- Pleural Effusion, Malignant
(etiology, surgery)
- Pleurisy
(etiology, surgery)
- Pneumonectomy
- Prognosis
- Retrospective Studies
- Survival Rate
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