Abstract | AIM: This study constitutes a revision of the guidelines for the treatment of major depressive disorder (MDD) issued by the Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) 2006. In incorporates changes in the experts׳ consensus that occurred between 2006 and 2012 as well as information regarding newly developed and recently published clinical trials. METHODS: Using a 44-item questionnaire, an expert consensus was obtained on pharmacological treatment strategies for (1) non-psychotic MDD, (2) psychotic MDD, (3) dysthymia and depression subtypes, (4) continuous and maintenance treatment, and (5) special populations; consensus was also obtained regarding (6) the choice of an antidepressant (AD) in the context of safety and adverse effects, and (7) non-pharmacological biological therapies. RESULTS: CONCLUSION: The pharmacological treatment strategy of KMAP-DD 2012 is similar to that of KMAP-DD 2006; however, the preference for the first-line use of AAPs was stronger in 2012 than in 2006.
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Authors | Jeong Seok Seo, Hoo Rim Song, Hwang Bin Lee, Young-Min Park, Jeong-Wan Hong, Won Kim, Hee-Ryung Wang, Eun-Sung Lim, Jong-Hyun Jeong, Duk-In Jon, Kyung Joon Min, Young Sup Woo, Won-Myong Bahk |
Journal | Journal of affective disorders
(J Affect Disord)
Vol. 167
Pg. 312-21
( 2014)
ISSN: 1573-2517 [Electronic] Netherlands |
PMID | 25010375
(Publication Type: Consensus Development Conference, Journal Article, Practice Guideline, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 Elsevier B.V. All rights reserved. |
Chemical References |
- Antidepressive Agents
- Antipsychotic Agents
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Topics |
- Adolescent
- Adult
- Aged
- Algorithms
- Antidepressive Agents
(therapeutic use)
- Antipsychotic Agents
(therapeutic use)
- Bipolar Disorder
(drug therapy)
- Child
- Comorbidity
- Depression, Postpartum
(drug therapy)
- Depressive Disorder
(diagnosis, drug therapy, psychology)
- Depressive Disorder, Major
(drug therapy)
- Drug Therapy, Combination
- Dysthymic Disorder
(drug therapy)
- Female
- Humans
- Male
- Middle Aged
- Premenstrual Dysphoric Disorder
(drug therapy)
- Republic of Korea
- Young Adult
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