Abstract |
For the first time TFAA/H3PO4 has facilitated the direct and metal-free N-acylation of carbazoles leading to a number of N-acylated derivatives. Several of these compounds were found to be promising when tested for their anti-proliferative properties against oral cancer cell lines.
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Authors | Sunder Kumar Kolli, Bagineni Prasad, P Vijaya Babu, Mohd Ashraf Ashfaq, Nasreen Z Ehtesham, R Ramesh Raju, Manojit Pal |
Journal | Organic & biomolecular chemistry
(Org Biomol Chem)
Vol. 12
Issue 32
Pg. 6080-4
(Aug 28 2014)
ISSN: 1477-0539 [Electronic] England |
PMID | 25006860
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Acetic Anhydrides
- Carbazoles
- Carboxylic Acids
- Fluoroacetates
- Phosphoric Acids
- Small Molecule Libraries
- trifluoroacetic anhydride
- phosphoric acid
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Topics |
- Acetic Anhydrides
(chemistry)
- Acylation
- Carbazoles
(pharmacology)
- Carboxylic Acids
(chemistry)
- Cell Line, Tumor
- Cell Proliferation
(drug effects)
- Fluoroacetates
(chemistry)
- HEK293 Cells
- Humans
- Neoplasms
(pathology)
- Phosphoric Acids
(chemistry)
- Small Molecule Libraries
(chemistry, pharmacology)
- Stereoisomerism
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