Abstract | OBJECTIVE: METHODS: RESULTS: Warning bleeding was found to be a significant factor protecting against neonatal RDS/TTN (p = 0.049). The cortisol levels in the umbilical vein were significantly higher in the cases of previa with warning bleeding than in those without warning bleeding (p = 0.020) and significantly higher in the no RDS/TTN cases than in the RDS/TTN cases (p = 0.040). CONCLUSIONS: Warning bleeding increases the cortisol level in cases of placenta previa. We suggest that genital bleeding may induce stress for both the mother and fetus, resulting in increased cortisol production, thus functioning as a protective factor against neonatal respiratory disorders.
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Authors | Hiroyuki Tsuda, Tomomi Kotani, Seiji Sumigama, Yukio Mano, Li Hua, Fumitaka Kikkawa |
Journal | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
(J Matern Fetal Neonatal Med)
Vol. 28
Issue 9
Pg. 1057-60
(Jun 2015)
ISSN: 1476-4954 [Electronic] England |
PMID | 25001429
(Publication Type: Journal Article)
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Chemical References |
- Biomarkers
- Arginine Vasopressin
- Hydrocortisone
- Norepinephrine
- Epinephrine
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Topics |
- Adult
- Arginine Vasopressin
(blood)
- Biomarkers
(blood)
- Epinephrine
(blood)
- Female
- Fetal Blood
(metabolism)
- Humans
- Hydrocortisone
(blood)
- Infant, Newborn
- Male
- Norepinephrine
(blood)
- Placenta Previa
(blood)
- Pregnancy
- Retrospective Studies
- Sex Factors
- Transient Tachypnea of the Newborn
(blood)
- Uterine Hemorrhage
(etiology)
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