Abstract | INTRODUCTION: MATERIALS AND METHODS: Forty-seven hemodialysis patients underwent the IGRA and TST tests. Demographic data and blood samples were collected and chest radiography was done for all participants. RESULT: Abnormal chest radiography was reported in 24% of the study group. The IGRA and TST were positive in 11 (23.4%) and 20 patients (43.5%), respectively. The agreement coefficient (kappa) between the IGRA and TST was 0.31. Positive TSTs were significantly associated with male sex and abnormal chest radiography. Diabetes mellitus was a risk factor for a positive IGRA result (P = .01). CONCLUSIONS: The IGRA test is not a sensitive test for detection of latent tuberculosisin hemodialysis patients residing in high-prevalence areas. We suggest that assessment of cellular immunity response in end-stage renal disease patient be a priority before reliance on the IGRA test result.
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Authors | Shokoufeh Savaj, Javad Savoj, Mitra Ranjbar, Foroogh Sabzghabaei |
Journal | Iranian journal of kidney diseases
(Iran J Kidney Dis)
Vol. 8
Issue 4
Pg. 329-32
(Jul 2014)
ISSN: 1735-8604 [Electronic] Iran |
PMID | 25001140
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Adult
- Aged
- Diabetic Nephropathies
(complications)
- Female
- Humans
- Interferon-gamma Release Tests
- Iran
- Kidney Failure, Chronic
(complications, therapy)
- Kidney Transplantation
- Latent Tuberculosis
(complications, diagnosis)
- Lung
(diagnostic imaging)
- Male
- Middle Aged
- Preoperative Care
- Radiography
- Renal Dialysis
- Sensitivity and Specificity
- Sex Factors
- Tuberculin Test
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