Abstract |
In the face of growing controversy about the utility of genetic mouse models of human disease, Rothwell et al. report on a shared mechanism by which two different neuroligin-3 mutations, associated with autism spectrum disorders in humans, produce an enhancement in motor learning. The open question is how much we can learn about human ills from such models.
|
Authors | Steven E Hyman |
Journal | Cell
(Cell)
Vol. 158
Issue 1
Pg. 13-4
(Jul 03 2014)
ISSN: 1097-4172 [Electronic] United States |
PMID | 24995974
(Publication Type: Journal Article, Comment)
|
Copyright | Copyright © 2014 Elsevier Inc. All rights reserved. |
Chemical References |
- Cell Adhesion Molecules, Neuronal
- Membrane Proteins
- Nerve Tissue Proteins
- neuroligin 3
|
Topics |
- Animals
- Autistic Disorder
(genetics, physiopathology)
- Cell Adhesion Molecules, Neuronal
(genetics)
- Humans
- Membrane Proteins
(genetics)
- Nerve Tissue Proteins
(genetics)
|