Recurrence of nephrocalcinosis after renal transplantation in an adult patient with primary hyperoxaluria type I.

Abstract

The medical history of a 42-year-old patient with primary hyperoxaluria type I is presented. Primary hyperoxaluria was suspected after renal transplantation, when oxalate deposits were found in a biopsy of the kidney graft. Diagnosis of type I hyperoxaluria was confirmed by the finding that significantly increased amounts of glycolic acid and oxalic acid were excreted. Treatment of the patient with 500 mg pyridoxine daily resulted in a decrease of the excretion of oxalate to normal values.

• Authors: G Knols, K M Leunissen, L J Spaapen, F T Bosman, T W vd Wiel, G Kootstra, J P van Hooff
• Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (Nephrol Dial Transplant) Vol. 4 Issue 2 Pg. 137-9 ( 1989) ISSN: 0931-0509 [Print] England
• PMID: 2496356 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Female
• Graft Survival
• Humans
• Hyperoxaluria (complications)
• Hyperoxaluria, Primary (complications, pathology)
• Kidney (pathology)
• Kidney Transplantation
• Kidney Tubules (pathology)
• Nephrocalcinosis (etiology, pathology)
• Recurrence