Disseminated Cunninghamella bertholletiae infection with spinal epidural abscess in a kidney transplant patient: case report and literature review.

Abstract

Cunninghamella bertholletiae is a rare cause of invasive mucormycosis. We report the case of a 42-year-old Thai woman who suffered from disseminated C. bertholletiae infection. The patient developed dry cough, sharp shooting pain in the left buttock referred to the left leg, and fever 1 month after undergoing deceased-donor kidney transplantation. Radiographic studies exhibited multiple pulmonary cavities, osteomyelitis of the sacral spine, epidural abscess along the lumbrosacral spine, and paravertebral soft tissue involvement. Surgical debridement of the epidural abscess concurrent with prolonged intravenous administration of amphotericin B resulted in a good outcome.

• Authors: O Navanukroh, A Jitmuang, M Chayakulkeeree, P Ngamskulrungroj
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 16 Issue 4 Pg. 658-65 (Aug 2014) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 24962170 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Chemical References

• Antifungal Agents

Topics

• Adult
• Antifungal Agents (therapeutic use)
• Cunninghamella (isolation & purification)
• Epidural Abscess (drug therapy, microbiology, surgery)
• Female
• Humans
• Kidney Transplantation (adverse effects)
• Mucormycosis (drug therapy, microbiology)