Abstract | BACKGROUND: OBJECTIVE: To analyze BSC and MBCC separately, evaluate whether they are distinct tumor subtypes, and analyze Mohs micrographic surgery (MMS) efficacy for BSC and MBCC. METHODS: Retrospective review of medical records and histologic specimens was conducted for 293 patients with 303 biopsy-proven BSCs or MBCCs treated with MMS between 1996 and 2004. In total, 32 BSCs and 128 MBCCs were identified. Surgical and follow-up data were analyzed. RESULTS: Kaplan-Meier estimates of recurrence-free survival after MMS were 100% at one year for both tumor subtypes and were 100% for BSC and 93.8% for MBCC at 5 years. Initial mean sizes were 1.5 cm for BSC and 1.3 cm for MBCC. Approximately 7% represented recurrent tumors at surgery. Of six patients with recurrences, none had known metastatic disease. LIMITATIONS: Limitations include retrospective design, analysis of only head and neck sites, and small sample sizes. CONCLUSION: BSC and MBCC showed no significant distinguishing characteristics to separate them into two BCC subtypes. Reported recurrence rates for BSC and MBCC are 12-45% with wide local excision; estimated recurrence rates are 4.1% with MMS. Our study showed recurrence-free survival of 95.1% at five years. Hence, MMS is effective in treating these BCC subtypes.
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Authors | Kattie J Allen, Mark A Cappel, Jill M Killian, Jerry D Brewer |
Journal | International journal of dermatology
(Int J Dermatol)
Vol. 53
Issue 11
Pg. 1395-403
(Nov 2014)
ISSN: 1365-4632 [Electronic] England |
PMID | 24961583
(Publication Type: Journal Article)
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Copyright | © 2014 The International Society of Dermatology. |
Topics |
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Basal Cell
(pathology, surgery)
- Carcinoma, Basosquamous
(pathology, surgery)
- Disease-Free Survival
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Mohs Surgery
- Neoplasm Recurrence, Local
(pathology)
- Skin Neoplasms
(pathology, surgery)
- Survival Rate
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