Trichoderma species fungemia after high-dose chemotherapy and autologous stem cell transplantation: a case report.

Abstract

We present a case of Trichoderma fungemia with pulmonary involvement in a multiple myeloma patient, who was severely immunocompromised and heavily treated with high-dose melphalan, and underwent autologous hematopoietic cell transplantation. This is the first report, to our knowledge, of proven Trichoderma fungemia, defined by published criteria, successfully treated with voriconazole.

• Authors: M Festuccia, L Giaccone, F Gay, L Brunello, E Maffini, F Ferrando, E Talamo, M Boccadoro, R Serra, A Barbui, B Bruno
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 16 Issue 4 Pg. 653-7 (Aug 2014) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 24920096 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Chemical References

• Antifungal Agents
• Antineoplastic Agents
• Voriconazole

Topics

• Antifungal Agents (therapeutic use)
• Antineoplastic Agents (administration & dosage, adverse effects)
• Fungemia (microbiology)
• Humans
• Male
• Middle Aged
• Mycoses (drug therapy, microbiology)
• Stem Cell Transplantation (adverse effects)
• Trichoderma (classification, isolation & purification)
• Voriconazole (therapeutic use)