Abstract | OBJECTIVE: To evaluate the effects of subarachnoid propofol administration (SPA) on analgesia, sedation, ataxia, cardiopulmonary, blood gas variables, and its application in ovariectomy in Jennies. STUDY DESIGN: Prospective, randomized, clinical trial. ANIMALS: Adult Jennies (n = 20; 100-120 kg; 5-7 years old). METHODS: In study 1, 5 Jennies had SPA (n = 5; group 1) through Tuohy catheter, and another 5 control Jennies had normal saline subarachnoid administration (n = 5; group 2). In study 2, 10 Jennies had SPA and ovariectomy (n = 10; group 3). In groups 1 and 3 analgesia, sedation and ataxia scores, cardiopulmonary and blood gas variables were recorded at different intervals before and after PSA. In group 2, only cardiopulmonary and blood gas variables were recorded. RESULTS: SPA produced pronounced analgesia, mild sedation and minimal ataxia. Heart rate (HR), respiratory rate (RR), pulse rate (PR), rectal temperature (RT), arterial blood pH, PaO2 , and PaCO2 were not significantly different from base line values after subarachnoid administration of either propofol or normal saline. CONCLUSION: SPA was found to be useful, efficient and feasible procedure for ovariectomy through standing flank laparotomy in Jennies.
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Authors | Mousa Daradka, Khreesha Ibtihal |
Journal | Veterinary surgery : VS
(Vet Surg)
Vol. 43
Issue 5
Pg. 569-73
(Jul 2014)
ISSN: 1532-950X [Electronic] United States |
PMID | 24909598
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | © Copyright 2014 by The American College of Veterinary Surgeons. |
Chemical References |
- Hypnotics and Sedatives
- Propofol
|
Topics |
- Anesthesia, Epidural
(veterinary)
- Animals
- Equidae
(physiology, surgery)
- Female
- Heart Rate
(drug effects)
- Hypnotics and Sedatives
(administration & dosage)
- Ovariectomy
(veterinary)
- Posture
- Propofol
(administration & dosage)
- Prospective Studies
- Subarachnoid Space
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