Abstract | OBJECTIVE: DATA SOURCES: We searched MEDLINE, PubMed, and Cochrane databases and found additional articles from bibliographies of relevant studies. METHODS OF STUDY SELECTION: TABULATION, INTEGRATION, AND RESULTS:
Pain scores were evaluated at the following times after extubation: 30 minutes, 1 hour, 2 hours, 4 hours, 8 hours, and 24 hours. The meta-analysis was based on random-effects methods for pooled data using RevMan. Postoperative pain decreased with the use of local anesthetic compared with placebo as follows (mean VAS decrease in millimeters, 95% confidence interval): 30 minutes 18.6 (11.7-25.5); 1 hour 16.6 (9.3-24.0); 2 hours 17.4 (9.6-25.2); 4 hours 12.5 (5.1-19.9); 8 hours 11.9 (6.7-17.1); and 24 hours 3.9 (-1.4 to 9.2). There was moderate heterogeneity in the data across studies (I statistic ranging from 55% to 75%). The effect size was similar for the following subgroups: pain scores reported as means or medians and use of McGill compared with VAS pain scales. A stratified analysis of trials including ring tubal ligation compared with clip tubal ligation showed the use of local anesthetic decreased pain substantially for both. No eligible studies assessed tubal ligation with cautery. CONCLUSION:
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Authors | Margo S Harrison, Marianne N DiNapoli, Carolyn L Westhoff |
Journal | Obstetrics and gynecology
(Obstet Gynecol)
Vol. 124
Issue 1
Pg. 68-75
(Jul 2014)
ISSN: 1873-233X [Electronic] United States |
PMID | 24901271
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Chemical References |
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Topics |
- Anesthetics, Local
(administration & dosage)
- Female
- Humans
- Laparoscopy
(methods)
- Pain Measurement
- Pain, Postoperative
(drug therapy)
- Randomized Controlled Trials as Topic
- Sterilization, Tubal
(methods)
- Surgical Instruments
- Treatment Outcome
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