Abstract | BACKGROUND: METHODS AND RESULTS: CONCLUSIONS:
|
Authors | Kristen J Bubb, Sarah L Trinder, Reshma S Baliga, Jigisha Patel, Lucie H Clapp, Raymond J MacAllister, Adrian J Hobbs |
Journal | Circulation
(Circulation)
Vol. 130
Issue 6
Pg. 496-507
(Aug 05 2014)
ISSN: 1524-4539 [Electronic] United States |
PMID | 24899690
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Copyright | © 2014 American Heart Association, Inc. |
Chemical References |
- 2-(3,4-dimethoxybenzyl)-7-(1-(1-hydroxyethyl)-4-phenylbutyl)-5-methylimidazo(5,1-f)(1,2,4)triazin-4 (3H)-one
- Imidazoles
- Phosphodiesterase Inhibitors
- Triazines
- Cyclic AMP
- Cyclic Nucleotide Phosphodiesterases, Type 2
- Cyclic GMP
|
Topics |
- Animals
- Cells, Cultured
- Cyclic AMP
(physiology)
- Cyclic GMP
(physiology)
- Cyclic Nucleotide Phosphodiesterases, Type 2
(antagonists & inhibitors, physiology)
- Humans
- Hypertension, Pulmonary
(drug therapy, enzymology)
- Imidazoles
(pharmacology, therapeutic use)
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Phosphodiesterase Inhibitors
(pharmacology, therapeutic use)
- Rats
- Rats, Sprague-Dawley
- Signal Transduction
(drug effects, physiology)
- Triazines
(pharmacology, therapeutic use)
|