Abstract | BACKGROUND: METHODOLOGY: RESULTS: Thirty patients with proximal lower limb deep vein thrombosis were treated with catheter-directed thrombolysis. Mean age of the study patients was 41.7 ± 15 years. Mean duration of illness was 13.3 ± 12 days. The mean duration of thrombolysis was 4.5 ± 1.3 days. Grade III (complete) lysis was achieved in 10 (33%) and Grade II (50-90%) lysis in 20 (67%) of patients. Patients with significant residual lesion in Grade II lysis following catheter-directed thrombolysis underwent percutaneous transluminal angioplasty alone (12/20) or venous stenting (8/20). All patients improved clinically following catheter-directed thrombolysis or assisted catheter-directed thrombolysis. Four patients (13%) developed pulmonary embolism during course of hospital stay and among them two (6.5%) patients died. Eleven patients (37%) had minor bleeding or hematoma at local site, and seven (23%) developed anemia requiring blood transfusion and four (13%) patients had thrombocytopenia. After six months, iliofemoral patency was found in 20 (72%) and post-thrombotic syndrome was seen in six (21%) patients. Two (6.5%) patients died during follow-up due to nephrotic syndrome and carcinoma breast. CONCLUSION:
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Authors | S Patra, B C Srinivas, C M Nagesh, B Reddy, C N Manjunath |
Journal | Phlebology
(Phlebology)
Vol. 30
Issue 7
Pg. 441-8
(Aug 2015)
ISSN: 1758-1125 [Electronic] England |
PMID | 24898308
(Publication Type: Clinical Trial, Journal Article)
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Copyright | © The Author(s) 2014. |
Topics |
- Adult
- Aged
- Angioplasty
- Female
- Humans
- Lower Extremity
(blood supply)
- Male
- Mechanical Thrombolysis
- Middle Aged
- Prospective Studies
- Venous Thrombosis
(therapy)
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