Wolf's Isotopic Response: Report of a Case and Review of Literature.

Abstract

"Wolf's isotopic response" refers to the occurrence of a new dermatosis at the site of previously healed dermatosis. A number of factors including viral, neural, vascular, and immunologic factors have been implicated in the causation of this peculiar response but none has been proven conclusively. Here, we report a case where lichen planus developed at the site of dermatofibrosarcoma protruberans that had been previously treated with surgery and radiotherapy. We also put forth a hypothesis on the genesis of isotopic response considering the above mentioned factors.

• Authors: Rahul Mahajan, Dipankar De, Uma Nahar Saikia
• Journal: Indian journal of dermatology (Indian J Dermatol) Vol. 59 Issue 3 Pg. 275-82 (May 2014) ISSN: 1998-3611 [Electronic] India
• PMID: 24891660 (Publication Type: Journal Article)