Abstract | BACKGROUND:
Balneotherapy, although not a well-established dermatological treatment, is thought to have therapeutic properties for psoriasis and is used as an alternative treatment modality throughout the world. OBJECTIVE: To evaluate the mechanism underlying the therapeutic immunologic effects of thermomineral water. METHODS: RESULTS: The mineral water balneotherapy group showed faster improvement in skin erythema and scales than the distilled water bathing group. A substantial reduction was observed in the lesional mRNA levels of IL-17A and IL-23 in the mineral water group. Serum levels of IL-4 and IL-5 were significantly decreased in the mineral water group but not in the distilled water group. Normalized T cell proportions were observed after bathing. CONCLUSION:
|
Authors | Young Bok Lee, Jun Young Lee, Hye Jin Lee, Seong Taek Yun, Jong Tae Lee, Hong Jig Kim, Dong Soo Yu, So Youn Woo, Jin-Wou Kim |
Journal | Annals of dermatology
(Ann Dermatol)
Vol. 26
Issue 2
Pg. 221-30
(Apr 2014)
ISSN: 1013-9087 [Print] Korea (South) |
PMID | 24882978
(Publication Type: Journal Article)
|