Campylobacter fetus bacteremia with purulent pleurisy in a young adult with primary hypogammaglobulinemia.

Abstract

A 24-year-old man presented with fever and pleural effusion predominantly containing lymphocytes. Cultures of the pleural effusion and blood revealed Campylobacter fetus, and laboratory studies showed a low serum level of immunoglobulin. The patient was diagnosed with C. fetus pleuritis, bacteremia and primary hypogammaglobulinemia, and subsequent treatment with meropenem and immunoglobulin improved his condition. Although the underlying cause of the primary hypogammaglobulinemia remains unclear, the patient's status improved under immunoglobulin replacement therapy. C. fetus pleuritis is a rare infectious disease usually observed in immunocompromised hosts. We herein describe the first report of C. fetus pleuritis in a young adult with primary hypogammaglobulinemia.

• Authors: Keiko Yamagami, Tomoko Miyashita, Tomoyuki Nakamura, Michinori Shirano, Tadahiro Nakamura, Kazuaki Kameda, Masayoshi Nishijima, Masahiro Imanishi, Xi Yang, Hirokazu Kanegane
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 53 Issue 11 Pg. 1221-5 ( 2014) ISSN: 1349-7235 [Electronic] Japan
• PMID: 24881753 (Publication Type: Case Reports, Journal Article)

Chemical References

• Thienamycins
• Meropenem

Topics

• Agammaglobulinemia (complications)
• Bacteremia (etiology)
• Campylobacter Infections (etiology)
• Campylobacter fetus (isolation & purification)
• Empyema, Pleural (etiology)
• Humans
• Immunization, Passive
• Immunocompromised Host
• Lung (diagnostic imaging)
• Male
• Meropenem
• Pleural Effusion (microbiology)
• Pleurisy (diagnostic imaging, etiology)
• Radiography
• Thienamycins (therapeutic use)
• Young Adult