Abstract | BACKGROUND AND PURPOSE: MATERIALS AND METHODS: We randomly assigned 56 subjects to receive CT-guided transforaminal (15 men, 13 women; mean age, 52 years; range, 28-72 years) or facet (8 men, 20 women; mean, 44 years; range, 26-60 years) injections. The primary outcome was pain severity rated on a Visual Analog Scale (0-100). Secondary outcomes were the Neck Disability Index and the Medication Quantitative Scale. RESULTS: In the intention-to-treat and as-treated analyses, for a mean baseline score, facet injections demonstrated a significant pain score reduction of 45.3% (95% CI, 21.4-69.2) and 37.0% (95% CI, 9.2-64.7), while transforaminal injections showed a nonsignificant pain score reduction of 9.8% (95% CI, +11.5-31.2) and 17.8% (95% CI, +6.6-42.2). While facet injections demonstrated an improvement in the Neck Disability Index score of 24.3% (95% CI, +2.9-51.5) and 20.7% (95% CI, +6.2-47.6) as opposed to transforaminal injections of 9.6% (95% CI, +15.2-34.4) and 12.8% (95% CI, +11.2-36.7), the results were not statistically significant. Noninferiority of facet to transforaminal injections was demonstrated for baseline pain scores of ≤60, while noninferiority analysis was inconclusive for baseline pain scores of ≥80 and for the Neck Disability Index. Neither intervention showed a significant medication-intake score reduction with time. CONCLUSIONS:
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Authors | N J Bureau, T Moser, J H Dagher, D Shedid, M Li, P Brassard, B E Leduc |
Journal | AJNR. American journal of neuroradiology
(AJNR Am J Neuroradiol)
Vol. 35
Issue 8
Pg. 1467-74
(Aug 2014)
ISSN: 1936-959X [Electronic] United States |
PMID | 24874533
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | © 2014 by American Journal of Neuroradiology. |
Chemical References |
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Topics |
- Adrenal Cortex Hormones
(administration & dosage)
- Adult
- Aged
- Double-Blind Method
- Female
- Humans
- Injections, Epidural
(adverse effects, methods)
- Injections, Intra-Articular
(adverse effects, methods)
- Male
- Middle Aged
- Pain
(drug therapy, etiology)
- Pain Measurement
- Radiculopathy
(drug therapy)
- Treatment Outcome
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