Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni.

Abstract

AIMS:

Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence.

MATERIALS AND METHODS:

Dental patients who received amlodipine (N = 115), for more than 3 months were studied to determine the drug-induced gingival overgrowth. Clinical diagnosis of drug-induced overgrowth was verified by disappearance or decreased severity of gingival overgrowth after withdrawal of the causative drug.

RESULTS:

The prevalence rate of amlodipine-induced gingival hyperplasia among experimental patients was 3.4%, while it was not observed among the control subjects. Oral examination revealed gingival overgrowth as a lobular or nodular enlargement on interdental papilla located in the anterior interproximal regions.

CONCLUSIONS:

In this study, there was a significant relationship between gingival inflammation resulting from dental plaque and drug dosage, and hyperplasia.

• Authors: Avneesh Tejnani, Ameet Mani, Neha Kaur Sodhi, Alok Mehta, Sonal Gourkhede, Vinayak Thorat, Pramod Marawar
• Journal: Journal of Indian Society of Periodontology (J Indian Soc Periodontol) Vol. 18 Issue 2 Pg. 226-8 (Mar 2014) ISSN: 0972-124X [Print] India
• PMID: 24872633 (Publication Type: Journal Article)