Amantadine induced corneal edema in a patient with primary progressive freezing of gait.

Abstract

Amantadine is commonly used for Parkinsonism. However amantadine can induce adverse corneal reaction. Here we report a patient with primary progressive freezing of gait who had severe corneal edema associated with amantadine, which was reversible after discontinuation of the amantadine. This report alerts neurologists for this reversible but potentially critical corneal edema in patients with Parkinsonism who are receiving amantadine.

• Authors: Young Eun Kim, Ji Young Yun, Hui-Jun Yang, Han-Joon Kim, Mee Kum Kim, Won Ryang Wee, Beom S Jeon
• Journal: Journal of movement disorders (J Mov Disord) Vol. 6 Issue 2 Pg. 34-6 (Oct 2013) ISSN: 2005-940X [Print] Korea (South)
• PMID: 24868424 (Publication Type: Journal Article)