Effect of a new combined therapy with nano-carbonate apatite and CO2 laser on dentin hypersensitivity in an in situ model.

Abstract

OBJECTIVE:

The aim of this study was to determine the occluding effects of a combination of dentifrice containing nano-carbonate apatite (n-CAP) and CO2 laser on dentinal tubules, and to evaluate the acid resistance of this combination after 4 days of treatment, by using an in situ model.

BACKGROUND DATA:

The synergic effect of this combination was demonstrated in an in vitro study.

METHODS:

This was a two period crossover, single-blind, randomized, four-treatment, split-mouth study. Ten healthy participants wore lower intraoral appliances during the treatment period. Specimens were divided into the following four groups: no treatment (control group), tooth-brushing using 20% n-CAP dentifrice (n-CAP group), CO2 laser irradiation (laser group), and laser irradiation after n-CAP application (combined group). Occluding effects were evaluated on 2 days (days 1 and 2), and then acid challenge was performed using grape juice on 2 days (days 3 and 4). All of the specimen surfaces were evaluated by a scanning electron microscope.

RESULTS:

The combined group showed a better occluding effect than control group compared with other treatment groups, and this effect was 20% higher than that in the n-CAP group. Also, the combined group had the smallest open dentinal tubular area among all of the treatment groups.

CONCLUSIONS:

The combined therapy is a promising method for ensuring a long-lasting effect of dentin hypersensitivity treatment in clinical practice.

• Authors: Sun Young Han, Ji Sun Kim, Young Seok Kim, Ho Keun Kwon, Baek Il Kim
• Journal: Photomedicine and laser surgery (Photomed Laser Surg) Vol. 32 Issue 7 Pg. 394-400 (Jul 2014) ISSN: 1557-8550 [Electronic] United States
• PMID: 24854714 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Apatites
• Dentifrices
• carboapatite

Topics

• Apatites (administration & dosage)
• Cross-Over Studies
• Dentifrices (therapeutic use)
• Dentin Sensitivity (drug therapy)
• Humans
• Lasers, Gas
• Random Allocation
• Single-Blind Method