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Flow cytometric monitoring of the in vitro inhibition of the phosphorylation of CRKL and of SRC family kinases in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors.

AuthorsL Krupkova, R Mojzikova, J Novotny, J Gazdova, M Divoka, I Skoumalova, P Rohon, M Jarosova, K Indrak, E Faber, V Divoky
JournalInternational journal of laboratory hematology (Int J Lab Hematol) Vol. 37 Issue 1 Pg. e11-5 (Feb 2015) ISSN: 1751-553X [Electronic] England
PMID24845482 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Adaptor Proteins, Signal Transducing
  • Antineoplastic Agents
  • CRKL protein
  • Nuclear Proteins
  • Protein Kinase Inhibitors
  • src-Family Kinases
Topics
  • Adaptor Proteins, Signal Transducing (antagonists & inhibitors)
  • Antineoplastic Agents (pharmacology, therapeutic use)
  • Flow Cytometry
  • Humans
  • In Vitro Techniques
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive (drug therapy, metabolism)
  • Nuclear Proteins (antagonists & inhibitors)
  • Phosphorylation (drug effects)
  • Protein Kinase Inhibitors (pharmacology, therapeutic use)
  • src-Family Kinases (antagonists & inhibitors)

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