Determinants of uptake of third doses of oral polio and DTP vaccines in the Ibadan North Local Government Area of Nigeria.

Abstract

BACKGROUND:

High dropout rates in the uptake of oral polio vaccine (OPV) and DTP vaccine persist despite efforts to improve immunisation coverage. This study identified determinants of uptake of third doses of OPV3 and DTP3 among infants who received first doses of either or both vaccines at immunisation centres in the Ibadan North Local Government Area of Nigeria.

METHODS:

Using a cohort study design, 400 mother-child pairs were assessed. A semi-structured, interviewer-administered questionnaire was used to collect data from each participant who were followed up for 90 days. Dates of subsequent doses of the vaccines were recorded. Multivariate analysis was performed using the log-rank test and Cox's regression analysis to identify predictive factors.

RESULTS:

Only 43.5% (174/400) and 24.8% (89/359) of children completed the OPV3 and DTP3 vaccines, respectively. Factors predictive of uptake of OPV3 were first birth (HR=1.66, 95% CI 1.11-2.48) and attending a tertiary health facility (HR=2.27, 95% CI 1.41-3.65), while attending a secondary health facility was significant for DTP3 uptake (HR=2.43, 95% CI 1.30-4.61).

CONCLUSIONS:

Uptake of third doses of vaccines was influenced by the type of health facility attended and the child birth order. Efforts to reduce vaccination dropouts should include creation of awareness of the importance of completing immunisation schedules for children of higher birth orders as well as improved service delivery at health facilities.

• Authors: Akinola Ayoola Fatiregun, Emem Emmanuel Etukiren
• Journal: International health (Int Health) Vol. 6 Issue 3 Pg. 213-24 (Sep 2014) ISSN: 1876-3405 [Electronic] England
• PMID: 24844557 (Publication Type: Journal Article)
• Copyright: © The Author 2014. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: [email protected].

Chemical References

• Diphtheria-Tetanus-Pertussis Vaccine
• Poliovirus Vaccine, Oral

Topics

• Adult
• Child, Preschool
• Diphtheria-Tetanus-Pertussis Vaccine (administration & dosage)
• Female
• Health Knowledge, Attitudes, Practice
• Humans
• Immunization Schedule
• Infant
• Infant, Newborn
• Male
• Mothers (psychology)
• Nigeria
• Patient Compliance (psychology, statistics & numerical data)
• Patient Dropouts (statistics & numerical data)
• Poliovirus Vaccine, Oral (administration & dosage)
• Prospective Studies
• Regression Analysis
• Risk Factors
• Socioeconomic Factors
• Surveys and Questionnaires
• Young Adult