Abstract |
Transvaginal repair with mesh of pelvic organ prolapse (POP) provides women with the durability of a synthetic graft using the less-invasive route of vaginal surgery. However, morbidities such as mesh exposures are common and challenging to manage. Small intestinal submucosa (SIS) is a naturally occurring collagen matrix derived from porcine intestine. It contains growth factors and cytokines that promote healing of damaged tissue. This case report describes a large vaginal mesh exposure due to necrosis of the full thickness of the anterior vaginal wall. A remarkable and rapid regeneration of vaginal tissue over the exposed mesh was achieved with SIS placement after failure of treatment with vaginal estrogen for >6 months. Collagen scaffold is an effective, rapid, and minimally invasive treatment for large vaginal mesh exposures.
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Authors | Marianna Alperin |
Journal | International urogynecology journal
(Int Urogynecol J)
Vol. 25
Issue 11
Pg. 1597-9
(Nov 2014)
ISSN: 1433-3023 [Electronic] England |
PMID | 24832859
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Collagen
(therapeutic use)
- Female
- Humans
- Middle Aged
- Pelvic Organ Prolapse
(surgery)
- Postoperative Complications
(etiology, therapy)
- Surgical Mesh
(adverse effects)
- Tissue Scaffolds
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