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Growth hormone treatment in a patient with Hurler-Scheie syndrome.

Abstract
A female patient with known Hurler-Scheie syndrome, who underwent hematopoietic cell transplantation, presented with growth retardation and delayed puberty. She started growth hormone (GH) treatment at age 12.33 years, resulting in significantly improved linear growth and predicted adult height. We describe details of her clinical course and literature review of growth pattern as well as GH use in patients with mucopolysaccharidosis I.
AuthorsDouglas G Rogers, Nat Nasomyont
JournalJournal of pediatric endocrinology & metabolism : JPEM (J Pediatr Endocrinol Metab) Vol. 27 Issue 9-10 Pg. 957-60 (Sep 2014) ISSN: 2191-0251 [Electronic] Germany
PMID24825081 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Human Growth Hormone
Topics
  • Adolescent
  • Child
  • Female
  • Growth Disorders (complications, drug therapy)
  • Hematopoietic Stem Cell Transplantation
  • Human Growth Hormone (therapeutic use)
  • Humans
  • Mucopolysaccharidosis I (complications, drug therapy, therapy)
  • Puberty, Delayed (complications, drug therapy)
  • Treatment Outcome

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