Hiccups associated with switching from olanzapine to aripiprazole in a patient with paranoid schizophrenia.

Abstract

This article reports the case of a 29-year-old schizophrenic woman without somatic illness in whom switching from olanzapine to aripiprazole induced hiccups. Antipsychotics are thought to be effective in the treatment of hiccups; however, they have rarely been reported to induce hiccups. Within 24 hours of taking aripiprazole, the patient began having hiccups continuously. One week after the hiccups ceased, the patient resumed taking aripiprazole, and the hiccups began again. Although rare, this case study suggests that aripiprazole induces hiccups.

• Authors: Hikaru Hori, Jun Nakamura
• Journal: Clinical neuropharmacology (Clin Neuropharmacol) 2014 May-Jun Vol. 37 Issue 3 Pg. 88-9 ISSN: 1537-162X [Electronic] United States
• PMID: 24824665 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antipsychotic Agents
• Dopamine Agonists
• Piperazines
• Quinolones
• Serotonin 5-HT2 Receptor Agonists
• Benzodiazepines
• Aripiprazole
• Olanzapine

Topics

• Adult
• Antipsychotic Agents (adverse effects, therapeutic use)
• Aripiprazole
• Benzodiazepines (therapeutic use)
• Dopamine Agonists (adverse effects, therapeutic use)
• Drug Monitoring
• Female
• Hiccup (chemically induced)
• Humans
• Olanzapine
• Piperazines (adverse effects, therapeutic use)
• Quinolones (adverse effects, therapeutic use)
• Recurrence
• Schizophrenia, Paranoid (drug therapy)
• Serotonin 5-HT2 Receptor Agonists (adverse effects, therapeutic use)