Abstract | BACKGROUND: METHODS: A total of 61 patients (16 with lateral epicondylitis, 14 with patellar tendinopathy, 15 with insertional Achilles tendinopathy, and 16 with plantar fasciitis) were each administered a single injection of HA (up to 2.5 ml). Efficacy and safety were assessed by comparing the visual analog scale (VAS) for pain and local symptoms before injection (baseline) and at 1 week after injection. We also investigated the injectable volume by means of the difference in syringe weight before and after injection and by the judgment of the administering investigator. RESULTS: The injection of HA resulted in a change in VAS (mean ± SD) of -2.20 ± 2.26 cm for the four sites overall and -2.55 ± 2.43 cm for lateral epicondylitis, -2.01 ± 2.16 cm for patellar tendinopathy, -1.80 ± 1.91 cm for insertional Achilles tendinopathy, and -2.38 ± 2.61 cm for plantar fasciitis. The injection of HA also improved local symptoms in each site. It was also determined that 2.5 ml of HA can be injected in each of the four sites. CONCLUSION:
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Authors | Tsukasa Kumai, Takeshi Muneta, Akihiro Tsuchiya, Masaharu Shiraishi, Yoshitaka Ishizaki, Kazuya Sugimoto, Norihiro Samoto, Shinji Isomoto, Yasuhito Tanaka, Yoshinori Takakura |
Journal | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
(J Orthop Sci)
Vol. 19
Issue 4
Pg. 603-11
(Jul 2014)
ISSN: 1436-2023 [Electronic] Japan |
PMID | 24817495
(Publication Type: Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Achilles Tendon
- Adult
- Fasciitis, Plantar
(drug therapy)
- Female
- Humans
- Hyaluronic Acid
(administration & dosage)
- Injections
- Male
- Middle Aged
- Molecular Weight
- Patella
- Prospective Studies
- Tendinopathy
(drug therapy)
- Tennis Elbow
(drug therapy)
- Time Factors
- Young Adult
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