Abstract | OBJECTIVE: METHODS: Ninety women at 24-34weeks of singleton pregnancy with intact membranes and arrested preterm labor were randomly allocated to receive OMP (n=45) or placebo (n=45) daily until 37weeks or delivery, whichever was earlier. Outcome parameters were compared using Student t test, χ(2) test, Fisher exact test, and log-rank χ(2) test. RESULTS: OMP significantly prolonged the latency period (33.29±22.16 vs 23.07±15.42days; P=0.013). Log-rank analysis revealed a significant difference in mean time to delivery between the 2 groups (P=0.014). There were significantly fewer preterm births (33% vs 58%; P=0.034) and low birth weight neonates (37% vs 64%; P=0.017), and significantly higher mean birth weight (2.44±0.58 vs 2.14±0.47kg; P=0.009) in the OMP group. Perinatal outcomes and adverse effects were similar in the 2 groups. CONCLUSION:
|
Authors | Manju Choudhary, Amita Suneja, Neelam B Vaid, Kiran Guleria, M M A Faridi |
Journal | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
(Int J Gynaecol Obstet)
Vol. 126
Issue 1
Pg. 60-3
(Jul 2014)
ISSN: 1879-3479 [Electronic] United States |
PMID | 24807871
(Publication Type: Journal Article, Randomized Controlled Trial)
|
Copyright | Copyright © 2014. Published by Elsevier Ireland Ltd. |
Chemical References |
|
Topics |
- Administration, Oral
- Adult
- Double-Blind Method
- Female
- Humans
- Pregnancy
- Premature Birth
(prevention & control)
- Progesterone
(administration & dosage)
- Progestins
(administration & dosage)
- Tocolysis
(methods)
- Treatment Outcome
- Young Adult
|