HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The second Austrian benchmark study for blood use in elective surgery: results and practice change.

AbstractBACKGROUND:
Five years after the first Austrian benchmark study demonstrated relatively high transfusion rate and an abundance of nonindicated transfusions in elective surgeries, this study was conducted to investigate the effects of the first benchmark study.
STUDY DESIGN AND METHODS:
Data from 3164 patients undergoing primary unilateral total hip replacement (THR), primary unilateral noncemented total knee replacement (TKR), or coronary artery bypass graft (CABG) surgery at 15 orthopedic and six cardiac centers were collected and compared with the first study.
RESULTS:
Transfusion rates decreased in THR (41% to 30%) and TKR (41% to 25%), but remained unchanged in CABG surgery (57% vs. 55%) compared with the first study. More than 80% of all transfusions involved at least 2 units of red blood cells (RBCs). Marked variations were observed in transfusion rates among the centers. The prevalence of anemia was three times higher in patients who received transfusions versus those who did not. However, preoperative anemia was left untreated in the majority of patients. A considerable intercenter variability of RBC loss ranging from 26% to 43% in THR, from 24% to 40% in TKR, and from 30% to 49% in CABG procedures was observed.
CONCLUSION:
The second benchmark study demonstrates substantial intercenter variability and small but significant reductions in RBC transfusions and RBC loss. Even though the main independent predictors of transfusion were the relative lost RBC volume followed by the relative preoperative and the lowest relative postoperative hemoglobin, preoperative anemia was not adequately treated in many patients, underscoring the importance of patient blood management in these patients.
AuthorsHans Gombotz, Peter H Rehak, Aryeh Shander, Axel Hofmann
JournalTransfusion (Transfusion) Vol. 54 Issue 10 Pt 2 Pg. 2646-57 (Oct 2014) ISSN: 1537-2995 [Electronic] United States
PMID24805865 (Publication Type: Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't)
Copyright© 2014 AABB.
Chemical References
  • Hemoglobins
Topics
  • Aged
  • Anemia (epidemiology, therapy)
  • Arthroplasty, Replacement, Hip (statistics & numerical data)
  • Arthroplasty, Replacement, Knee (statistics & numerical data)
  • Austria (epidemiology)
  • Benchmarking (statistics & numerical data)
  • Blood Loss, Surgical (statistics & numerical data)
  • Blood Transfusion (standards, statistics & numerical data, trends)
  • Coronary Artery Bypass (statistics & numerical data)
  • Elective Surgical Procedures (statistics & numerical data)
  • Female
  • Hemoglobins
  • Humans
  • Male
  • Middle Aged
  • Perioperative Care (statistics & numerical data)
  • Practice Patterns, Physicians' (trends)
  • Predictive Value of Tests
  • Prevalence
  • Prospective Studies

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: