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Serpins shield tumor cells from antimetastatic brain defenses.

Abstract
Serpin expression in tumors facilitates brain metastasis by blocking the effects of plasmin.
Authors
JournalCancer discovery (Cancer Discov) Vol. 4 Issue 5 Pg. OF17 (May 2014) ISSN: 2159-8290 [Electronic] United States
PMID24795021 (Publication Type: Journal Article)
Chemical References
  • Serpins
  • Fibrinolysin
Topics
  • Animals
  • Brain Neoplasms (etiology, pathology, secondary)
  • Breast Neoplasms (genetics, pathology)
  • Female
  • Fibrinolysin (metabolism)
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Lung Neoplasms (genetics, pathology)
  • Serpins (metabolism)

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