Abstract |
Seborrheic dermatitis (SD) is generally treated with topical steroids, antifungals, or both. The aim of this study was to compare the efficacy of sertaconazole 2% cream vs. metronidazole 1% gel in the treatment of seborrheic dermatitis. A group of 156 patients suffering from SD were studied. The patients were randomly divided into two groups. The first group received local sertaconazole 2% cream and they were recommended to use the cream twice a day for 4 weeks. In the control group, thirty patients received metronidazole 1% gel twice a day for four weeks. At the point of referral, and also 2 and 4 weeks after the first visit, the patients were examined by a dermatologist to identify improvement of clinical symptoms. A higher level of satisfaction was observed after 28 days in the sertaconazole group (87.1%) than the metronidazole group (56.4%). Considering its efficacy, safety, and acceptability profiles, sertaconazole 2% cream is a worthwhile alternative to existing antifungal therapies for the treatment of seborrheic dermatitis.
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Authors | Mohamad Goldust, Elham Rezaee, Ramin Raghifar |
Journal | Annals of parasitology
(Ann Parasitol)
Vol. 59
Issue 4
Pg. 173-7
( 2013)
ISSN: 2299-0631 [Print] Poland |
PMID | 24791343
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Antifungal Agents
- Imidazoles
- Thiophenes
- Metronidazole
- sertaconazole
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Topics |
- Adolescent
- Adult
- Antifungal Agents
(administration & dosage, therapeutic use)
- Child
- Dermatitis, Seborrheic
(drug therapy)
- Double-Blind Method
- Female
- Humans
- Imidazoles
(administration & dosage, therapeutic use)
- Male
- Metronidazole
(administration & dosage, therapeutic use)
- Middle Aged
- Thiophenes
(administration & dosage, therapeutic use)
- Young Adult
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