Abstract | OBJECTIVES: Interstitial lung disease is a common finding in patients with the antisynthetase syndrome. High-resolution computed tomography is the reference test for diagnosis and follow-up of this condition, but it involves considerable radiation exposure. Our aim was to describe chest ultrasound features and its correlation with high-resolution computed tomography findings in a series of patients with the antisynthetase syndrome. METHODS: The study included patients from our antisynthetase syndrome cohort with varying degrees of interstitial lung disease, consulting in our outpatient clinic over a 1-year period. Chest high-resolution computed tomography and chest sonography were prospectively performed within a 1-week period. High-resolution computed tomography Warrick score was calculated and chest sonography findings (B-lines) at several sonographic points along the anterior and posterior intercostal spaces were semi-quantitatively analyzed. Rho Spearman statistics were applied for possible correlations. RESULTS: Twenty-one consecutive patients were studied. A median of 59 thoracic points was studied per patient (IQR 6); 44.1% (95% CI 29.9-60.7) of them showed at least one B-line. A correlation coefficient of 0.135 (p=0.5) was found between the percentage of ultrasound points with B-lines and the Warrick's score. Only the number of bronchopulmonary segments showing ground glass findings was associated with the percentage of sonographic points with B-lines (Rho=0.5, p=0.02). CONCLUSIONS: A good correlation between the percentage of sonographic points with B-lines and high-resolution computed tomography ground glass opacities was observed in patients with the antisynthetase syndrome.
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Authors | I Pinal Fernández, E Pallisa Núñez, A Selva-O'Callaghan, E Castella-Fierro, X Martínez-Gómez, Miquel Vilardell-Tarrés |
Journal | Clinical and experimental rheumatology
(Clin Exp Rheumatol)
Vol. 32
Issue 3
Pg. 404-7
( 2014)
ISSN: 0392-856X [Print] Italy |
PMID | 24773767
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Female
- Humans
- Lung
(diagnostic imaging)
- Lung Diseases, Interstitial
(diagnostic imaging)
- Male
- Middle Aged
- Multimodal Imaging
(methods)
- Myositis
(diagnostic imaging)
- Tomography, X-Ray Computed
(methods)
- Ultrasonography
(methods)
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